stderr:
Failed to resolve compatible artifacts from lock pants-lockfile.txt for 1 target:
1. cp310-cp310-linux_x86_64:
    Failed to resolve all requirements for abbreviated platform cp310-cp310-linux_x86_64 from pants-lockfile.txt:

Configured with:
    build: False
    use_wheel: True

Dependency on pyqt6-webengine-qt6 not satisfied, 1 incompatible candidate found:
1.) pyqt6-webengine-qt6 6.3.1 (via: pyqt6-webengine==6.3.1 -> PyQt6-WebEngine-Qt6>=6.3.0) does not have any compatible artifacts:
    <https://software-repository.ci-cd.aws.amramedical.com/pypi/pyqt6-webengine-qt6/6.3.1/PyQt6_WebEngine_Qt6-6.3.1-py3-none-manylinux_2_28_x86_64.whl>

PyQt6_WebEngine_Qt6-6.3.1-py3-none-manylinux_2_28_x86_64.whl

looks compatible to me?

manylinux_2_28

means glibc 2.28 or newer. Is that the case on the target Linux?

Indeed, doh!

Yes. It's really always the way to go. Platforms is a very old Pex hack that only works if you're lucky.