#15293 Failure to running requirement's binary scripts using subprocess.run or os.system or ... (FileNotFoundError: [Errno 2] No such file or directory: '...') Issue created by AlirezaRoshanzamir Bug description I believe this issue is very similar to the #12651 issue. Consider the following example:

.
├── BUILD
├── main.py
├── pants.toml
└── test_main.py

# pants.toml
[GLOBAL]
pants_version = '2.10.0'
backend_packages = ['pants.backend.python']

# BUILD
python_requirement(name='python_requirement', requirements=['cowsay'])
python_sources(name='python_sources')
python_tests(name='python_tests')

# main.py
import subprocess
import cowsay

def cowsay_hello_using_subprocess():
    subprocess.run(['cowsay', 'hello'])

def cowsay_hello_using_module():
    cowsay.cow('hello')

# test_main.py
import main

def test_cowsay_hello_using_subprocess():
    main.cowsay_hello_using_subprocess()

def test_cowsay_hello_using_module():
    main.cowsay_hello_using_module()

Running the

./pants test :python_tests

results

1 failed, 1 passed

. The

test_cowsay_hello_using_subprocess

test fails:

FileNotFoundError: [Errno 2] No such file or directory: 'cowsay'

Actually, a similar issue occurred if we define

pex_binary

for the source code. But, thanks to #12651, using

execution_mode='venv'

solves the issue there. In my opinion, there should be a similar solution for the intermediate pex files created for other goals and targets. Am I thinking right? Pants version: 2.10.0 OS: Ubuntu 20.04.3 LTS pantsbuild/pants